Sandra Isabelle Irwin Depew, 77, of Seneca passed away at home on Saturday, October 23, 2025. Born on July 2, 1948, in Grove City, Sandra was the daughter of the late Louis and Mary Irwin. On December 19, 1975 Sandra married Robert Depew who survives. Sandra enjoyed reading old cookbooks, cooking and baking, and most of all spending time with her family. Along with her husband Sandra is survived by her children: John broad of slippery rock, Paula (Cash) Murray of Slippery Rock, Laura (Chuck) Weber of Grove City, Kimberly (Jerry) McKinney of Slippery Rock and Lisa (Brian) Rodgers of Westley; seven grandchildren, eight great grandchildren, and her siblings Margaret (John) Bennit of Harrisville, JoAnn (Dan) Baker of Saegertown and Louis Irwin Jr. of Barkeyville. Sandra was preceded in death by her parents and two baby brothers. Private funeral services were held by the family. Interment was held at the Barkeyville Cemetery. Friends and family can email condolences by visiting www.jamisonfuneralhome.com
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